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Cell Regeneration
Fig. 2 | Cell Regeneration

Fig. 2

From: Continuous immunosuppression is required for suppressing immune responses to xenografts in non-human primate brains

Fig. 2

The infiltration of CD3+ T and CD19+ B lymphocytes into human grafts. A, B Immunofluorescent analysis of CD3+ T (arrow) and CD19+ B (arrowhead) lymphocytes in human grafts of Mk #1 at 4 months, Mk #2 at 8 months, and Mk #3 at 12 months p.t. with continuous CsA treatment, and Mk #4 at 10 months p.t. with discontinuous CsA treatment. Cell nuclei were counterstained with DAPI. C, D Percentages of CD3+ T and CD19+ B lymphocytes in human grafts of Mk #1, Mk #2, Mk #3, and Mk#4 shown in (A and B). Scale bars: 50 μm in (A, B). Data are represented as the mean ± SEM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, ns (not significant)

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