Table 1 Panel of inhibitor compounds screened for inhibition of DNA binding activity of 15 transcription factors
From: Exploring the utility of organo-polyoxometalate hybrids to inhibit SOX transcription factors
POMs | Chemical formula | Type | Organic side chain | Mol.wt |
|---|---|---|---|---|
D1Mo | K6 [P2Mo18O62] | Dawson | None | 3016 |
D1W | K6 [P2W18O62] | Dawson | None | 4597 |
D2 | (NC16H36)7 α1-[P2W17O62SnC6H8N4] | Dawson | Aliphatic | 6089 |
D3 | (NC16H36)7 α2-[P2W17O62SnC16H23N3O2] | Dawson | Val-Val-Val | 6357 |
D4 | (NC16H36)7 α2-[P2W17O62SnC6H11N4O] | Dawson | Aliphatic | 6135 |
D5 | (NC16H36)6 α2-[P2W17O61SnC4H10] | Dawson | Aliphatic | 5794 |
D6 | (NC16H36)6 α2-[P2W17O62SnC3H4O2] | Dawson | Aliphatic | 5810 |
D7 | (NC16H36)7 α1-[P2W17O66SnC24H34N4] | Dawson | Trp-Ala-Leu | 6438 |
D8 | (NC16H36)7 α1-[P2W17O66SnC22H32] | Dawson | Phe-Ala-Leu | 6356 |
D9 | (NC16H36)6 α1-[P2W17O61SnC4H10] | Dawson | Aliphatic | 5794 |
D10 | (NC16H36)7 α2-[P2W17O62SnC6H8N4] | Dawson | Aliphatic | 6089 |
K1Mo | Na3 [PMo12O40] | Keggin | None | 1892 |
K1W | Na3 [PW12O40] | Keggin | None | 2946 |
decaV | (NC16H36)3 [H3V10O28] | Decavandate | None | 1688 |
metaW | Na6W12O39 · xH2O | Sodium metatungstate | None | 2969 |
MoO 4 2− | Na2MoO4 · 2H2O | Sodium Molybdate | None | 206 |