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Cell Regeneration
Fig. 2 | Cell Regeneration

Fig. 2

From: Consistent apparent Young’s modulus of human embryonic stem cells and derived cell types stabilized by substrate stiffness regulation promotes lineage specificity maintenance

Fig. 2

Cytoskeletal organization and focal adhesion formation in hESCs and HepaRG cells on different substrate stiffness. a, b Cytoskeletal organization (arrows = actin stress fibers) and c, d vinculin formation (arrows = elongated clusters, with locally enlarged vinculin clusters) in hESCs a and c and HepaRG cells b and d during culture on different substrates. Scale bars = 10 μm. e, f Quantitative analysis of vinculin clusters per cell in hESCs and HepaRG cells over the culture period. *P < 0.05

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