Fig. 1From: Organoid based personalized medicine: from bench to bedsideComparison of cell lines, patient-derived xenografts and organoids. Cell lines have low cost, are easy to handle and can be applied to multiple experimental techniques. PDXs preserve tumor heterogeneity and tumor-stromal interactions. PDOs can be derived from both epithelial cancer cells and normal epithelium and cultured in an extracellular matrix (ECM) -providing basement membrane extractBack to article page