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Cell Regeneration
Fig. 1 | Cell Regeneration

Fig. 1

From: The roles and activation of endocardial Notch signaling in heart regeneration

Fig. 1

Schematic diagram of the Notch signaling pathway showing the ligand, receptor and translocation of the NICD domain. ADAM, a disintegrin and metalloproteinase; ANK, ankyrin repeats; Co-R, corepressor; CSL, CBF1/Su(H)/Lag-1; DSL, Delta/Serrate/Lag-2 motif; MAML, mastermind-like; NICD, Notch intracellular domain; NLS, nuclear localization sequence; NRR, negative regulatory region; PEST, proline/glutamic acid/serine/threonine-rich sequence; RAM, RBPJκ-associated module; TMD, transmembrane domain

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