Skip to main content
Fig. 2 | Cell Regeneration

Fig. 2

From: Proteins in DNA methylation and their role in neural stem cell proliferation and differentiation

Fig. 2

The connections between DNMT1 and TET1. a DNMT1 maintains DNA methylation during proliferation by methylating hemimethylated CpG sites into full-methylated. TET1 has higher abilities to demethylate hemimethylated CpG sites than full-methylated. b Passive DNA demethylation by inhibiting DNMT1 leads to lower increase in chromatin accessibility and gene expression than active DNA demethylation by stimulating TET1

Back to article page