Fig. 2

Summary of miRNAs regulating heart regeneration. Different miRNAs and their targets stimulating (red area) or inhibiting (green area) cardiomyocyte proliferation and heart regeneration were shown. miRNAs are grouped according to the amount of evidence supporting their function: (1) miRNAs with evidence regulating heart regeneration in vivo (MI model) and cardiomyocyte proliferation in vitro; (2) miRNAs with evidence regulating cardiomyocyte proliferation both in vivo (without MI model) and in vitro; (3) miRNAs with only in vitro results of regulating cardiomyocyte proliferation. These three groups were indicated by different depth of red and green colors. MI: myocardial infarction