Fig. 4

mOLs within the retina are divided in an asymmetric manner. a Serial imaging showed that the mOL within the retina was under division. Arrows indicate the processes that maintained integrity during the whole imaging. b The olig2⁺ cell within the retina is in a mature state, as shown by the perfect myelin structure. c Schematic picture shows the method to calculate cell displacement in the asymmetric division of mOL. The origin point is the crossover of two random myelin processes. d The displacement of the mother and daughter cells in the asymmetric division of mOLs within the retina. Arrows show the time point at which division was completed. e Speeds of mother and daughter cells. Daughter cells had a high migration ability while mother cells did not (p < 0.05). f-i BrdU results show that a mOL within the retina was proliferating, while the myelin structure remained integral (arrows). The image has 10 slices, and the interval is 0.5 μm. Scale bar: 10 μm (a-b); 5 μm (f-i)