Fig. 2
From: Regulation and dysregulation of hair regeneration: aiming for clinical application
Dysregulation of hair regeneration in AGA. A Clinical presentation of a patient with AGA. B Androgen receptors (AR) in the hair follicle dermal papilla sense androgen and promote Dkk1 and TGF-β expression, which retard hair growth. TGF-β further shrinks the blood vessel. AR signaling also antagonizes Wnt/β-catenin signaling in the HF. C GWAS results showing the potential genes involved in AGA and their chromosomal locations. D List of current treatment options for AGA and the possible mechanisms