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Fig. 3 | Cell Regeneration

Fig. 3

From: Interferon-beta inhibits human glioma stem cell growth by modulating immune response and cell cycle related signaling pathways

Fig. 3

Merged images showing the relative expression level of S100-β and the increased size of the cell nucleus after IFN-β stimulation. a Representative overlapping images showing staining for Ki67/DAPI, S100-β/DAPI, Sox2/DAPI, Ki67/S100-β, and Sox2/S100-β in hGCSs. Three groups, control, 11 ng/mL, and 33 ng/mL IFN-β treatment groups (yellow frames indicate enlarged areas). b Representative images from (a) at higher magnification. White arrows indicate S100-β expression. Enlarged area (scale bar, 50 μm). c Representative images of DAPI staining and a schematic diagram of the nucleus. d Quantitative analysis of nuclear size, as measured using ImageJ. Scale bar, 50 μm. Data are presented as the mean ± SD. Student’s t-test. p < 0.001

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