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Fig. 2 | Cell Regeneration

Fig. 2

From: Glioma stem cells and neural stem cells respond differently to BMP4 signaling

Fig. 2

Transcriptional changes in human glioma stem cells (hGSCs) and human neural stem cells (hNSCs) after BMP treatment. a Gene clustering from control (Con-1 and Con-2) and BMP treatment (BMP-1 and BMP-2) in hGSCs/hNSCs RNA sequencing results show significantly upregulated and downregulated genes as hGSCs+ (1574 genes), hGSCs− (1352 genes), hNSCs+ (1517 genes) and hNSCs− (1635 genes). b The Venn diagram shows the overlap of 4 gene lists in (a) to identify hGSCs-hNSCsNA (331 genes) and hGSCs+hNSCsNA (402 genes) lists. c Cell differentiation and cell proliferation pathways were identified in Gene Ontology analysis of hGSCs and hNSCs gene list. Expression patterns of hGSCs+hNSCsNA (83 genes)/hGSCs−hNSCsNA (89 genes) in cell differentiation and hGSCs+hNSCsNA (69 genes) in cell proliferation were shown as heatmap. d Detailed expression patterns of top 30 genes in hGSCs+hNSCsNA and hGSCs−hNSCsNA were shown as heatmap

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