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Fig. 1 | Cell Regeneration

Fig. 1

From: Physiological and molecular mechanisms of insect appendage regeneration

Fig. 1

Diagram of appendage regeneration in insects. Following injury or amputation, appendage regeneration in nymphal legs (A and B) or larval imaginal discs (C) proceeds through a generally similar process involving three stages: wound healing, blastema formation, and morphogenesis (regenerative growth, differentiation, and patterning). A In some Blattaria and other orders of insects, when amputation is performed at a site proximal to the femur, a new leg can be regenerated under the exoskeleton after one molt. B In some insects of the order Orthoptera, regeneration mainly occurs at the distal site of the tibia. Four molting cycles are needed for the successful regeneration of missing tissue. C After the surgical amputation of the imaginal leg disc, the smaller fragment from the anterior dorsal quadrant regenerates the remainder of the disc, and a new leg can be regenerated after one molt. Co, coxa; Tr, trochanter; Fe, femur; Ti, tibia; Ta, tarsus

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