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Fig. 1 | Cell Regeneration

Fig. 1

From: In vivo generation and regeneration of β cells in zebrafish

Fig. 1

Cell sources for in vivo generation of β cells in zebrafish. Cells in the extrapancreatic duct linking the pancreas to the gut (EPD) differentiate into endocrine progenitor cells that form the ventrally derived β cells in the principal islet. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that differentiates into progenitors of acinar, ductal, and endocrine cells. Under certain conditions, new β cells can be generated through transdifferentiation, neogenesis and proliferation

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