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Cell Regeneration
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  2. The CCCTC-binding factor (CTCF) protein and its modified forms regulate gene expression and genome organization. However, information on CTCF acetylation and its biological function is still lacking. Here, we ...

    Authors: Shixin Gong, Gongcheng Hu, Rong Guo, Jie Zhang, Yiqi Yang, Binrui Ji, Gang Li and Hongjie Yao
    Citation: Cell Regeneration 2022 11:34
    Content type: Research article Published on:

  3. Human-mouse chimeras offer advantages for studying the pathophysiology of human cells in vivo. Chimeric mouse brains have been created by engrafting human fetal tissue- or pluripotent stem cell-derived progeni...

    Authors: Peng Jiang and Mahabub Maraj Alam
    Citation: Cell Regeneration 2022 11:32
    Content type: Opinion Published on:

  7. Reprogramming somatic cells to pluripotent stem cells has revolutionized the biomedical field by providing enormous hopes and opportunities for the regeneration of tissues and organs for transplantation. Using...

    Authors: Deepti Abbey
    Citation: Cell Regeneration 2022 11:27
    Content type: Research highlight Published on:

  8. Mouse embryonic stem cells (mESCs) cycle in and out of a transient 2-cell (2C)-like totipotent state, driven by a complex genetic circuit involves both the coding and repetitive sections of the genome. While a...

    Authors: Lu Li, Pishun Li, Jiale Chen, Li Li, Yunfan Shen, Yangzixuan Zhu, Jiayi Liu, Lu Lv, Song Mao, Fang Chen, Guang Hu and Kai Yuan
    Citation: Cell Regeneration 2022 11:25
    Content type: Research article Published on:

  9. Pancreatic β cells differentiated from stem cells provide promise for cell replacement therapy of diabetes. Human pluripotent stem cells could be differentiated into definitive endoderm, followed by pancreatic...

    Authors: Wenwen Jin and Wei Jiang
    Citation: Cell Regeneration 2022 11:24
    Content type: Review Published on:

    The Correction to this article has been published in Cell Regeneration 2022 11:30

  10. Malignant Glioma is characterized by strong self-renewal potential and immature differentiation potential. The main reason is that malignant glioma holds key cluster cells, glioma stem cells (GSCs). GSCs contr...

    Authors: Xin-Xin Han, Shengkai Jin, Li-Ming Yu, Min Wang, Xin-Yu Hu, Dai-Yu Hu, Jie Ren, Meng-Han Zhang, Wei Huang, Jia-Jia Deng, Qing-Qing Chen, Zhengliang Gao, Hua He and Chunhui Cai
    Citation: Cell Regeneration 2022 11:23
    Content type: Research article Published on:

  12. Mesenchymal stem cells (MSCs)-based therapy has displayed some promises in ischemia heart diseases although its efficacy may be affected by changes in surrounding environments. This study evaluated the role of...

    Authors: Xing Qin, Juanjuan Fei, Yu Duan, Asli F. Ceylan, Fuyang Zhang and Jun Ren
    Citation: Cell Regeneration 2022 11:21
    Content type: Research article Published on:

  14. Adult mammalian cardiomyocytes are unable to proliferate to regenerate lost tissue after heart injury. Du et al., reporting in Cell Stem Cell, employ a FUCCI- and MADM-based system to screen for small molecules c...

    Authors: Nevan Powers and Guo N. Huang
    Citation: Cell Regeneration 2022 11:20
    Content type: Research highlight Published on:

  15. Animal models are widely used for biomedical studies and drug evaluation. The small intestine plays key roles in nutrient absorption, hormone secretion, microbiota defense and drug absorption and metabolism. A...

    Authors: Haonan Li, Xiaodan Wang, Yalong Wang, Mengxian Zhang, Fan Hong, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji and Ye-Guang Chen
    Citation: Cell Regeneration 2022 11:19
    Content type: Research article Published on:

  17. Bioprinting has exhibited remarkable promises for the fabrication of functional skin substitutes. However, there are some significant challenges for the treatment of full-thickness skin defects in clinical pra...

    Authors: Changmei Niu, Liyang Wang, Dongdong Ji, Mingjun Ren, Dongxu Ke, Qiang Fu, Kaile Zhang and Xi Yang
    Citation: Cell Regeneration 2022 11:10
    Content type: Research article Published on:

  20. Long non-coding (lnc) RNA plays important roles in many cellular processes. The function of the vast majority of lncRNAs remains unknown. Here we identified that lncRNA-1700113A16RIK existed in skeletal muscle...

    Authors: Xin Fu, Sheng Li, Minzhi Jia, Bo Xu, Lele Yang, Ruimiao Ma, Hong Cheng, Wenjun Yang and Ping Hu
    Citation: Cell Regeneration 2022 11:13
    Content type: Research article Published on:

  21. Adult skeletal muscle stem cells, also known satellite cells (SCs), are a highly heterogeneous population and reside between the basal lamina and the muscle fiber sarcolemma. Myofibers function as an immediate...

    Authors: Hu Li, Lin Kang, Rimao Wu, Changyin Li, Qianying Zhang, Ran Zhong, Lijing Jia, Dahai Zhu and Yong Zhang
    Citation: Cell Regeneration 2022 11:11
    Content type: Research article Published on:

    The Correction to this article has been published in Cell Regeneration 2022 11:17

  22. The Chchd10 gene encodes a coiled-coil-helix-coiled-coil-helix-domain containing protein predicted to function in the mitochondrion and nucleus. Mutations of Chchd10 are associated with ALS, dementia and myopathy...

    Authors: Wei Xia, Jiamin Qiu, Ying Peng, Madigan M. Snyder, Lijie Gu, Kuilong Huang, Nanjian Luo, Feng Yue and Shihuan Kuang
    Citation: Cell Regeneration 2022 11:14
    Content type: Research article Published on:

  23. Myocardial regeneration has been considered a promising option for the treatment of adult myocardial injuries. Previously, a chick early amniotic fluid (ceAF) preparation was shown to contain growth-related fa...

    Authors: Baiping Cui, Yufan Zheng, Xiang Gao, Lihong Zhang, Borui Li, Jia Chen, Xinyan Zhou, Mengyuan Cai, Wenrui Sun, Yuting Zhang, Keejong Chang, Jiayi Xu, Fuyin Zhu, Yan Luo, Tao Sun, Jin Qian…
    Citation: Cell Regeneration 2022 11:9
    Content type: Research article Published on:

  25. Long non-coding RNAs (lncRNAs) are important regulators of diverse biological processes, especially skeletal muscle cell differentiation. Most of the lncRNAs identified to date are localized in the nucleus and...

    Authors: Lili Zhai, Xin Wan, Rimao Wu, Xiaohua Yu, Hu Li, Ran Zhong, Dahai Zhu and Yong Zhang
    Citation: Cell Regeneration 2022 11:8
    Content type: Research article Published on:

  26. Early human brain development can be affected by multiple prenatal factors that involve chemical exposures in utero, maternal health characteristics such as psychiatric disorders, and cancer. Breast cancer is one...

    Authors: Kangli Cui, Wenwen Chen, Rongkai Cao, Yingying Xie, Peng Wang, Yunsong Wu, Yaqing Wang and Jianhua Qin
    Citation: Cell Regeneration 2022 11:7
    Content type: Report Published on:

  28. Cell metabolism plays vital roles in organismal development, but it has been much less studied than transcriptional and epigenetic control of developmental programs. The difficulty might be largely attributed ...

    Authors: Ting Li, Yejun Zou, Shuning Liu, Yi Yang, Zhuo Zhang and Yuzheng Zhao
    Citation: Cell Regeneration 2022 11:5
    Content type: Review Published on:

  31. The liver has remarkable capability to regenerate, employing mechanism to ensure the stable liver-to-bodyweight ratio for body homeostasis. The source of this regenerative capacity has received great attention...

    Authors: Wenjuan Pu and Bin Zhou
    Citation: Cell Regeneration 2022 11:2
    Content type: Review Published on:

    The Correction to this article has been published in Cell Regeneration 2022 11:12

  32. Studying the etiology of human neurodevelopmental diseases has long been a challenging task due to the brain’s complexity and its limited accessibility. Human pluripotent stem cells (hPSCs)-derived brain organ...

    Authors: Xiaoxiang Lu, Jiajie Yang and Yangfei Xiang
    Citation: Cell Regeneration 2022 11:1
    Content type: Review Published on:

  36. Information about the dynamic change and post-injury regeneration of cervical epithelium is relatively rare, even though it is tightly related to gynecologic malignancy. Here, using a feeder cell-based culturi...

    Authors: Zixian Zhao, Yujia Wang, Yingchuan Wu, Dandan Li, Ting Zhang, Yu Ma, Xiaoming Teng and Wei Zuo
    Citation: Cell Regeneration 2021 10:36
    Content type: Research article Published on:

  37. The evolution of pluripotent stem cell-derived retinal organoids (ROs) has brought remarkable opportunities for developmental studies while also presenting new therapeutic avenues for retinal diseases. With a ...

    Authors: Xiao Zhang, Wen Wang and Zi-Bing Jin
    Citation: Cell Regeneration 2021 10:33
    Content type: Review Published on:

  39. Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses. Organoids have been shown to be promising models for dru...

    Authors: Haonan Li, Yalong Wang, Mengxian Zhang, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji and Ye-Guang Chen
    Citation: Cell Regeneration 2021 10:32
    Content type: Methodology Published on:

  41. Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this stud...

    Authors: Yuan Zhao, Tianyu Wang, Yanqi Zhang, Liang Shi, Cong Zhang, Jingyuan Zhang, Jiao Yao, Qianyu Chen, Xiaofen Zhong, Yanxing Wei, Yongli Shan and Guangjin Pan
    Citation: Cell Regeneration 2021 10:30
    Content type: Research article Published on:

  44. Building human organs in a dish has been a long term goal of researchers in pursue of physiologically relevant models of human disease and for replacement of worn out and diseased organs. The liver has been an...

    Authors: Do Thuy Uyen Ha Lam, Yock Young Dan, Yun-Shen Chan and Huck-Hui Ng
    Citation: Cell Regeneration 2021 10:27
    Content type: Review Published on:

  45. Tissue engineering has provided new treatment alternatives for tissue reconstruction. Advances in the tissue engineering field have resulted in mechanical support and biological substitutes to restore, maintai...

    Authors: Nicole Andréa Corbellini Henckes, Dalana Faleiro, Laura Chao Chuang and Elizabeth Obino Cirne-Lima
    Citation: Cell Regeneration 2021 10:26
    Content type: Review Published on:

  48. Microanatomy of the vast majority of human organs at birth is characterized by marked differences as compared to adult organs, regarding their architecture and the cell types detectable at histology. In preter...

    Authors: D. Fanni, C. Gerosa, C. Loddo, M. Castagnola, V. Fanos, M. Zaffanello and G. Faa
    Citation: Cell Regeneration 2021 10:22
    Content type: Review Published on:

  49. Forkhead box (Fox) transcription factors play important roles in mammalian development and disease. However, their function in mouse somatic cell reprogramming remains unclear. Here, we report that FoxD subfam...

    Authors: Meijun Fu, Huan Chen, Zepo Cai, Yihang Yang, Ziyu Feng, Mengying Zeng, Lijun Chen, Yue Qin, Baomei Cai, Pinghui Zhu, Chunhua Zhou, Shengyong Yu, Jing Guo, Jing Liu, Shangtao Cao and Duanqing Pei
    Citation: Cell Regeneration 2021 10:17
    Content type: Research article Published on:

  50. Increasing evidence suggest functional roles of subepithelial mesenchymal niche cells in maintaining intestinal stem cells and in modulating the pathogenesis of various intestinal diseases in mammals. A recent...

    Authors: Guoli Zhu and Rongwen Xi
    Citation: Cell Regeneration 2021 10:24
    Content type: Research Highlight Published on:
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  • ISSN: 2045-9769 (electronic)

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