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  1. The BMP (Bone morphogenetic protein) signaling pathway plays a central role in metazoan biology, intricately shaping embryonic development, maintaining tissue homeostasis, and influencing disease progression. ...

    Authors: Wei Zhou, Kun Yan and Qiaoran Xi
    Citation: Cell Regeneration 2023 12:37
  2. Naïve pluripotent state can be obtained by several strategies from various types of cells, in which the cell fate roadmap as well as key biological events involved in the journey have been described in detail....

    Authors: Zhifen Tu, Yan Bi, Tengyan Mao, Hong Wang, Shaorong Gao and Yixuan Wang
    Citation: Cell Regeneration 2023 12:35
  3. Human pluripotent stem cells (hPSCs) have been suggested as a potential source for the production of blood cells for clinical application. In two decades, almost all types of blood cells can be successfully ge...

    Authors: Haiqiong Zheng, Yijin Chen, Qian Luo, Jie Zhang, Mengmeng Huang, Yulin Xu, Dawei Huo, Wei Shan, Ruxiu Tie, Meng Zhang, Pengxu Qian and He Huang
    Citation: Cell Regeneration 2023 12:31

    The Correction to this article has been published in Cell Regeneration 2023 12:32

  4. Paracrine signals play pivotal roles in organ homeostasis. Mesenchymal stromal cells (MSCs) play a key role in regulating epithelium homeostasis in the intestine while their paracrine effects are poorly charac...

    Authors: Siting Wei, Meng Li, Wanlu Song, Jiaye Liu, Shicheng Yu, Yalong Wang, Mengxian Zhang, Huijun Du, Yuan Liu, Huidong Liu, Wei Fu, Baojie Li and Ye-Guang Chen
    Citation: Cell Regeneration 2023 12:30

    The Correction to this article has been published in Cell Regeneration 2023 12:34

  5. As an important part of the stomach, gastric antrum secretes gastrin which can regulate acid secretion and gastric emptying. Although most cell types in the gastric antrum are identified, the comparison of cel...

    Authors: Xiaodan Wang, Fan Hong, Haonan Li, Yalong Wang, Mengxian Zhang, Shibo Lin, Hui Liang, Hongwen Zhou, Yuan Liu and Ye-Guang Chen
    Citation: Cell Regeneration 2023 12:27
  6. Ischemia–reperfusion injury occurs after reperfusion treatment for patients suffering myocardial infarction, however the underlying mechanisms are incompletely understood and effective pharmacological interven...

    Authors: Yuanyuan Chen, Jianyong Du, Lixia Zheng, Zihao Wang, Zongwang Zhang, Zhengyuan Wu, Xiaojun Zhu and Jing-Wei Xiong
    Citation: Cell Regeneration 2023 12:25
  7. Intestinal cancer is one of the most frequent and lethal types of cancer. Modeling intestinal cancer using organoids has emerged in the last decade. Human intestinal cancer organoids are physiologically releva...

    Authors: Hanqing Lin, Yalong Wang, Chunyan Cheng, Yuxin Qian, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu-Xia Deng, Bing Zhao, Jiani Cao, Lei Wang, Liu Wang, Lingmin Liang, Wenli Kelly Chen, Chunping Yu…
    Citation: Cell Regeneration 2023 12:24
  8. Organoids have attracted great interest for disease modelling, drug discovery and development, and tissue growth and homeostasis investigations. However, lack of standards for quality control has become a prom...

    Authors: Yalong Wang, Hanqing Lin, Lianzheng Zhao, Fan Hong, Jie Hao, Zhen Zhang, Weiqi Sheng, Linhong Song, Chu-Xia Deng, Bing Zhao, Jiani Cao, Lei Wang, Liu Wang, Lingmin Liang, Wenli Kelly Chen, Chunping Yu…
    Citation: Cell Regeneration 2023 12:23
  9. High-throughput phenotypic screening is a cornerstone of drug development and the main technical approach for stem cell research. However, simultaneous detection of activated core factors responsible for cell ...

    Authors: Jun Li, Jun Chi, Yang Yang, Zhongya Song, Yong Yang, Xin Zhou, Yang Liu and Yang Zhao
    Citation: Cell Regeneration 2023 12:22
  10. The regeneration capacity after an injury is critical to the survival of living organisms. In animals, regeneration ability can be classified into five primary types: cellular, tissue, organ, structure, and wh...

    Authors: Yun Zhao, Chong Gao, Xue Pan and Kai Lei
    Citation: Cell Regeneration 2023 12:14
  11. Adipose tissues are essential for actively regulating systemic energy balance, glucose homeostasis, immune responses, reproduction, and longevity. Adipocytes maintain dynamic metabolic needs and possess hetero...

    Authors: Jiayin Ye, Cheng Gao, Yong Liang, Zongliu Hou, Yufang Shi and Ying Wang
    Citation: Cell Regeneration 2023 12:13

    The Correction to this article has been published in Cell Regeneration 2023 12:20

  12. Hematopoietic stem cells (HSCs) are critical for the treatment of a variety of hematological diseases. However, the low number of HSCs lead to the clinical application difficult. To gain more functional human ...

    Authors: Guixian Liang and Feng Liu
    Citation: Cell Regeneration 2023 12:18
  13. Steatosis, as the early stage of nonalcoholic fatty acid disease (NAFLD), would progress into nonalcoholic steatohepatitis (NASH) and liver failure without intervention. Despite the development of animal model...

    Authors: Jinsong Wei, Wen Zhang and Bing Zhao
    Citation: Cell Regeneration 2023 12:17
  14. EAF1 and EAF2, the eleven-nineteen lysine-rich leukemia (ELL)-associated factors which can assemble to the super elongation complex (AFF1/4, AF9/ENL, ELL, and P-TEFb), are reported to participate in RNA polyme...

    Authors: WenYe Liu, ShuHui Lin, LingYa Li, ZhiPeng Tai and Jing-Xia Liu
    Citation: Cell Regeneration 2023 12:10
  15. Liver is an organ with notable capacity of regeneration. Reprogramming of hepatocytes towards an immature state is one of the important mechanisms for hepatocyte replenishment. Inflammatory response mediated b...

    Authors: Ruopu Li, Deqiang Li and Yu Nie
    Citation: Cell Regeneration 2023 12:16
  16. Spinal motor neurons deficiency results in a series of devastating disorders such as amyotrophic lateral sclerosis (ALS), spinal muscular atrophy (SMA) and spinal cord injury (SCI). These disorders are current...

    Authors: He Jax Xu, Yao Yao, Fenyong Yao, Jiehui Chen, Meishi Li, Xianfa Yang, Sheng Li, Fangru Lu, Ping Hu, Shuijin He, Guangdun Peng and Naihe Jing
    Citation: Cell Regeneration 2023 12:15
  17. Preclinical models that can accurately predict the toxicity and efficacy of candidate drugs to human liver tissue are in urgent need. Human liver organoid (HLO) derived from human pluripotent stem cells offers...

    Authors: Xiaoshan Wu, Dacheng Jiang, Yi Yang, Shuang Li and Qiurong Ding
    Citation: Cell Regeneration 2023 12:6
  18. Regeneration, as a fascinating scientific field, refers to the ability of animals replacing lost tissue or body parts. Many metazoan organisms have been reported with the regeneration phenomena, but showing ev...

    Authors: Jiru Zhong, Andi Jing, Shaojuan Zheng, Sheng Li, Xiaoshuai Zhang and Chonghua Ren
    Citation: Cell Regeneration 2023 12:9
  19. Spatial transcriptomics, which combine gene expression data with spatial information, has quickly expanded in recent years. With application of this method in liver research, our knowledge about liver develop...

    Authors: Jia He, Chengxiang Deng, Leonard Krall and Zhao Shan
    Citation: Cell Regeneration 2023 12:11
  20. The overlapping roles of Hippo and Hedgehog signaling in biological functions and diseases prompt us to investigate their potential interactions. Activation of Hippo signaling enhances the transcriptional outp...

    Authors: Chao Tang, Jirong Wang, Minli Yao, Xing Ji, Wei Shi, Chengyun Xu, Ling-Hui Zeng and Ximei Wu
    Citation: Cell Regeneration 2023 12:3
  21. Inflammatory bowel disease (IBD) is a chronic inflammatory condition caused by multiple genetic and environmental factors. Numerous genes are implicated in the etiology of IBD, but the diagnosis of IBD is chal...

    Authors: Shicheng Yu, Mengxian Zhang, Zhaofeng Ye, Yalong Wang, Xu Wang and Ye-Guang Chen
    Citation: Cell Regeneration 2023 12:8
  22. De novo organ regeneration is the process in which adventitious roots or shoots regenerate from detached or wounded organs. De novo organ regeneration can occur either in natural conditions, e.g. adventitious roo...

    Authors: Qihui Wan, Ning Zhai, Dixiang Xie, Wu Liu and Lin Xu
    Citation: Cell Regeneration 2023 12:1
  23. Myelopoiesis is the process in which the mature myeloid cells, including monocytes/macrophages and granulocytes, are developed. Irregular myelopoiesis may cause and deteriorate a variety of hematopoietic malig...

    Authors: Yang-Xi Hu and Qing Jing
    Citation: Cell Regeneration 2023 12:2
  24. Deer antlers constitute a unique mammalian model for the study of both organ formation in postnatal life and annual full regeneration. Previous studies revealed that these events are achieved through the proli...

    Authors: Hengxing Ba, Xin Wang, Datao Wang, Jing Ren, Zhen Wang, Hai-Xi Sun, Pengfei Hu, Guokun Zhang, Shengnan Wang, Chao Ma, Yusu Wang, Enpeng Wang, Liang Chen, Tianbin Liu, Ying Gu and Chunyi Li
    Citation: Cell Regeneration 2022 11:43
  25. Cell fate transition is a fascinating process involving complex dynamics of three-dimensional (3D) chromatin organization and phase separation, which play an essential role in cell fate decision by regulating ...

    Authors: Xiaoru Ling, Xinyi Liu, Shaoshuai Jiang, Lili Fan and Junjun Ding
    Citation: Cell Regeneration 2022 11:42
  26. Skeletal muscle plays a critical role in human health. Muscle stem cells (MuSCs) serve as the major cell type contributing to muscle regeneration by directly differentiating to mature muscle cells. MuSCs usual...

    Authors: Xin Fu, Cheng-le Zhuang and Ping Hu
    Citation: Cell Regeneration 2022 11:40
  27. Intestinal organoids, derived from intestinal stem cell self-organization, recapitulate the tissue structures and behaviors of the intestinal epithelium, which hold great potential for the study of development...

    Authors: Fanlu Meng, Congcong Shen, Li Yang, Chao Ni, Jianyong Huang, Kaijun Lin, Zanxia Cao, Shicai Xu, Wanling Cui, Xiaoxin Wang, Bailing Zhou, Chunyang Xiong, Jihua Wang and Bing Zhao
    Citation: Cell Regeneration 2022 11:39
  28. Malignant glioma is a highly heterogeneous and invasive primary brain tumor characterized by high recurrence rates, resistance to combined therapy, and dismal prognosis. Glioma stem cells (GSCs) are likely res...

    Authors: Xin-Xin Han, Chunhui Cai, Li-Ming Yu, Min Wang, Wenhan Yang, Dai-Yu Hu, Jie Ren, Lu-Ying Zhu, Jia-Jia Deng, Qing-Qing Chen, Hua He and Zhengliang Gao
    Citation: Cell Regeneration 2022 11:36
  29. Central nervous system (CNS) neurons typically fail to regenerate their axons after injury leading to neurological impairment. Axonal regeneration is a highly energy-demanding cellular program that requires lo...

    Authors: Ning Huang and Zu-Hang Sheng
    Citation: Cell Regeneration 2022 11:33
  30. Cilia are microtubule-based organelles projected from most eukaryotic cell surfaces performing cell motility and signaling. Several previously recognized non-ciliary proteins play crucial roles in cilium forma...

    Authors: Kaiming Xu and Guangshuo Ou
    Citation: Cell Regeneration 2022 11:29

    The Correction to this article has been published in Cell Regeneration 2022 11:41

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