Fig. 1
From: Cardiac cell type-specific responses to injury and contributions to heart regeneration
Cell type-specific responses to cardiac injury. a The outer surface and luminal surface of the myocardium is covered by epicardial cells and endocardial cells, respectively. Fibroblasts reside between cardiomyocytes within the myocardium. After injury, the activation of epicardial cell, endocardial cells, fibroblasts, and immune cells, together with proliferation of cardiomyocytes, contribute to heart regeneration. b Summary of activated signaling pathways after injury and applications in animal models