Skip to main content
Cell Regeneration
Fig. 1 | Cell Regeneration

Fig. 1

From: Activation of the Melanocortin-4 receptor signaling by α-MSH stimulates nerve-dependent mouse digit regeneration

Fig. 1

Mc4r-GFP and α-MSH expression in limb nerve tissues. a-h Representative images of Mc4r-GFP and βIII-tubulin expression detected by immunofluorescence staining, on sections of E10.5 forelimb (FL) (a), E11.5 forelimb (b,c), E11.5 hindlimb (HL) (d), E12.5 forelimb (e,f) and E13.5 hindlimb (g,h). i-p Images of Mc4r-GFP and α-MSH staining, on sections adjacent to those shown in a-h. Sagittal sections of the limb are shown distal to the left, except c,e,k,m are transverse sections of the embryo through the forelimb. (h,p) are high magnification images of areas outlined in (g, o). Arrowheads indicate Mc4r-GFP positive nerve tissues. Arrows (in e, m) indicate dorsal ramus (dr). bp, basal plate; vr, ventral ramus; fp, floor plate; FL, forelimb; HL, hindlimb. Scale bars are 200 μm, except for (h), 50 μm and (p), 25 μm

Back to article page