Skip to main content
Cell Regeneration
Fig. 1 | Cell Regeneration

Fig. 1

From: Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium

Fig. 1

Generation of the transcriptional atlases of cross-species ileum epithelial cells. A, B, H&E staining on ileum sections (A) and quantitation of the length of villus (B) from human, macaque, pig, rat and mouse. Scale bars, 100 μm. Data are displayed as the mean ± SD by one-way ANOVA. 50 villus regions were calculated for the length in B. The significance was displayed by each species compared to human. *P < 0.05, **P < 0.01, ***P < 0.001. C, UMAP plots showing different cell types from 9988 ileum epithelial cells from human, macaque, pig, rat and mouse. D, Dot Plot showing cell type-specific genes, colored by relative gene expression. Each dot represents a gene and the size shows the percentage of cells expressing this gene. E, UMAP plot of ileum epithelial cells grouped by species. The red circles point differential cell types across species, including Paneth cells and CA7+ cells, respectively

Back to article page