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Cell Regeneration
Fig. 5 | Cell Regeneration

Fig. 5

From: Beclin1 haploinsufficiency compromises mesenchymal stem cell-offered cardioprotection against myocardial infarction

Fig. 5

Ultrastructural myocardial and mitochondrial properties of area-at-risk myocardium from WT and BECN+/− mice following MI with or without MSCs transplantation. a Representative TEM ultrastructural images from all mouse groups; b Percentage of damaged mitochondria; c mitochondrial circularity (short axis/long axis); d PGC1α levels; and e UCP2 levels. Insets: Representative immunoblots depicting PGC1α and UCP2 using specific antibodies (GAPDH or α-Tubulin as loading controls); Mean ± SEM, n = 5–6 mice or 19–29 mitochondria from 5 TEM images (panel c) per group, * p < 0.05 between indicated groups

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