Fig. 1

Zebrafish myelopoiesis and recently acknowledged regulators. Zebrafish myeloid cells derives from myeloid progenitor cells and hematopoietic stem cells. The sites each hematopoietic wave takes place are indicated together with timelines, as are some of the recently reported regulators of zebrafish myelopoiesis. The promotive and suppressive regulators are labelled in red and blue, respectively. RBI, rostral blood island; ALM, anterior lateral mesoderm; EC, endothelial cell; MPC, myeloid progenitor cell; PBI, post blood island; EMP, erythroid-myeloid progenitor; DA, dorsal aorta; CHT, caudal hematopoietic tissue; HEC, hemogenic endothelial cell; HSC, hematopoietic stem cell; CMP, common myeloid progenitor