Dr. Bing Zhao (Fudan University, China)
Dr. Xin-Hua Feng (Zhejiang University, China)
Dr. Ye-Guang Chen (Tsinghua University, China; Nanchang University, China)
A thematic series in Cell Regeneration.
Signaling is the ability of cells to receive and transmit signals via different transduction pathways and respond to such inputs, with which a single cell or multi-cellular system can communicate with the environment, as well as among each other. Each signaling is modulated to serve for specific cellular response and behavior, and the regulatory network and crosstalk among different pathways that integrate different inputs and modulate the dynamics of signals play an essential role in directing the cellular or multi-cellular functions, such as self-renewal and differentiation. Deregulation of signaling pathways in stem cells is associated with many pathological conditions, including development disorders. A better understanding of the molecular mechanisms of the signaling is a significant basis to develop novel regenerative therapeutic strategies.
To advance basic and translational research in this important field, Cell Regeneration is inviting submissions to its upcoming special issue on “Signaling in stem cell self-renewal and differentiation”.
We consider studies focusing on the various biological features and underlying mechanisms related to the signaling in embryonic stem cells, iPS and adult stem cells. Potential topics include, but are not limited to the signaling in the following processes:
- Stem cell stemness maintenance and differentiation
- Stem cell aging and rejuvenation
- Cell lineage hierarchy and fate determination
- Cell transdifferentiation, dedifferentiation, and reprogramming
- Cell division/loss and stem cell recruitment/dynamic filling in organ renewal
- Stem cell-based therapy
The Editor-in-Chief of Cell Regeneration will review all submissions prior to peer review and may reject any of them that do not fit the scope of the journal or do not meet the journal's standards for peer review. All articles of Thematic Series will undergo full, independent peer review, in line with the journal's ethical and editorial policies. There is no guarantee of acceptance, even for commissioned or invited papers. The journal’s Editor-in-Chief has a final authority on editorial content.