Skip to main content
Cell Regeneration
Download PDF

Correction to: CRISPR/Cas: a potential gene-editing tool in the nervous system

Cell Regeneration volume 10, Article number: 35 (2021) Cite this article

The Original Article was published on 06 August 2020

Correction to: Cell Regeneration (2020) 9:12

https://doi.org/10.1186/s13619-020–00,044-6

Following publication of the original article (Gao et al. 2020 [1]), it is reported that the “Background” section and the heading “Main Text” need to be added to the article.

The Background section has been provided below.

Background

The CRISPR/Cas system is gaining more and more popularity in gene editing and therapy since first discovered in 1987. Up to now, on one hand, different types of the CRISPR/Cas system were discovered to improve its size, editing efficiency and PAM limitations; on the other hand, by fusing different factors to the mutant Cas protein which inactivates its nuclease activity but retains its ability to bind a specific DNA target site by a guide RNA, different types of engineered CRISPR/Cas9 tools were developed to perform modification of a specific gene, like DNA methylation or demethylation, histone acetylation or deacetylation and so on. Here, we briefly introduce these tools and their applications in the nervous system.

The original article (Gao et al. 2020 [1]) has been updated.

Reference

  1. Gao Y, Gao K, Yang H. CRISPR/Cas: a potential gene-editing tool in the nervous system. Cell Regen. 2020;9:12. https://doi.org/10.1186/s131619-020-00044-6.

Download references

Author information

Authors and Affiliations

  1. Institute of Neuroscience, State Key Laboratory of Neuroscience, Key Laboratory of Primate Neurobiology, CAS Center for Excellence in Brain Science and Intelligence Technology, Shanghai Research Center for Brain Science and Brain-Inspired Intelligence, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, 200031, China

    Yanxia Gao, Kexin Gao & Hui Yang

Authors
  1. Yanxia Gao
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kexin Gao
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Hui Yang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hui Yang.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gao, Y., Gao, K. & Yang, H. Correction to: CRISPR/Cas: a potential gene-editing tool in the nervous system. Cell Regen 10, 35 (2021). https://doi.org/10.1186/s13619-021-00095-3

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s13619-021-00095-3