BMP members | Cancer type | Phenotype | References |
---|---|---|---|
BMP2 | Ovarian | Promote growth and stemness | Choi et al. 2015 |
Lung | Enhance stemness | Husanie et al. 2022 | |
Breast | Induce EMT and stemness | ||
BMP4 | Lung | Promote differentiation | Lee et al. 2014b |
DIPG | Inhibit stemness and growth | Sun et al. 2022 | |
GBM | Promote differentiation | Savary et al. 2013 | |
BMP5 | Colorectal | Inhibit stem cell-like properties, proliferation, migration, invasion | Chen et al. 2018 |
Breast | Reduce stemness | Jin et al. 2022 | |
BMP6 | Prostate | Induce differentiation | Lee et al. 2011 |
Medulloblastoma | Induce differentiation | Armandari et al. 2021 | |
BMP7 | Colorectal | Antiangiogenic and prodifferentiation | Veschi et al. 2020 |
Glioma | Promote differentiation and reduce stemness | ||
BMP8 | Gastric | Reduce differentiation | Wisnieski et al. 2017 |
BMP9 | GBM | Induce differentiation | Porcù et al. 2018 |
GDF6 | Melanoma | Prevent differentiation and cell death, promote tumor growth | |
AMH | Endometrial | Activate differentiation and inhibit tumor growth | Fortner et al. 2017 |
BMPR1A | CRC | Inhibit stem cell activation | Kodach et al. 2011 |
BMPR1B | GSC | Astroglial differentiation in GSCs | Lee et al. 2008 |
ACVR1A | DIPG | Promote stemness and progenitor cell arrest | |
BMPR2 | NSCLC | Increase cell migration and invasiveness | Wu et al. 2022 |