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Cell Regeneration
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  3. The liver has remarkable capability to regenerate, employing mechanism to ensure the stable liver-to-bodyweight ratio for body homeostasis. The source of this regenerative capacity has received great attention...

    Authors: Wenjuan Pu and Bin Zhou
    Citation: Cell Regeneration 2022 11:2
    Content type: Review Published on:

    The Correction to this article has been published in Cell Regeneration 2022 11:12

  4. Studying the etiology of human neurodevelopmental diseases has long been a challenging task due to the brain’s complexity and its limited accessibility. Human pluripotent stem cells (hPSCs)-derived brain organ...

    Authors: Xiaoxiang Lu, Jiajie Yang and Yangfei Xiang
    Citation: Cell Regeneration 2022 11:1
    Content type: Review Published on:

  8. Information about the dynamic change and post-injury regeneration of cervical epithelium is relatively rare, even though it is tightly related to gynecologic malignancy. Here, using a feeder cell-based culturi...

    Authors: Zixian Zhao, Yujia Wang, Yingchuan Wu, Dandan Li, Ting Zhang, Yu Ma, Xiaoming Teng and Wei Zuo
    Citation: Cell Regeneration 2021 10:36
    Content type: Research article Published on:

  9. The evolution of pluripotent stem cell-derived retinal organoids (ROs) has brought remarkable opportunities for developmental studies while also presenting new therapeutic avenues for retinal diseases. With a ...

    Authors: Xiao Zhang, Wen Wang and Zi-Bing Jin
    Citation: Cell Regeneration 2021 10:33
    Content type: Review Published on:

  11. Pig and monkey are widely used models for exploration of human diseases and evaluation of drug efficiency and toxicity, but high cost limits their uses. Organoids have been shown to be promising models for dru...

    Authors: Haonan Li, Yalong Wang, Mengxian Zhang, Hong Wang, Along Cui, Jianguo Zhao, Weizhi Ji and Ye-Guang Chen
    Citation: Cell Regeneration 2021 10:32
    Content type: Methodology Published on:

  13. Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the underlying molecular basis remains unclear. Here in this stud...

    Authors: Yuan Zhao, Tianyu Wang, Yanqi Zhang, Liang Shi, Cong Zhang, Jingyuan Zhang, Jiao Yao, Qianyu Chen, Xiaofen Zhong, Yanxing Wei, Yongli Shan and Guangjin Pan
    Citation: Cell Regeneration 2021 10:30
    Content type: Research article Published on:

  16. Building human organs in a dish has been a long term goal of researchers in pursue of physiologically relevant models of human disease and for replacement of worn out and diseased organs. The liver has been an...

    Authors: Do Thuy Uyen Ha Lam, Yock Young Dan, Yun-Shen Chan and Huck-Hui Ng
    Citation: Cell Regeneration 2021 10:27
    Content type: Review Published on:

  17. Tissue engineering has provided new treatment alternatives for tissue reconstruction. Advances in the tissue engineering field have resulted in mechanical support and biological substitutes to restore, maintai...

    Authors: Nicole Andréa Corbellini Henckes, Dalana Faleiro, Laura Chao Chuang and Elizabeth Obino Cirne-Lima
    Citation: Cell Regeneration 2021 10:26
    Content type: Review Published on:

  20. Microanatomy of the vast majority of human organs at birth is characterized by marked differences as compared to adult organs, regarding their architecture and the cell types detectable at histology. In preter...

    Authors: D. Fanni, C. Gerosa, C. Loddo, M. Castagnola, V. Fanos, M. Zaffanello and G. Faa
    Citation: Cell Regeneration 2021 10:22
    Content type: Review Published on:

  21. Forkhead box (Fox) transcription factors play important roles in mammalian development and disease. However, their function in mouse somatic cell reprogramming remains unclear. Here, we report that FoxD subfam...

    Authors: Meijun Fu, Huan Chen, Zepo Cai, Yihang Yang, Ziyu Feng, Mengying Zeng, Lijun Chen, Yue Qin, Baomei Cai, Pinghui Zhu, Chunhua Zhou, Shengyong Yu, Jing Guo, Jing Liu, Shangtao Cao and Duanqing Pei
    Citation: Cell Regeneration 2021 10:17
    Content type: Research article Published on:

  22. Increasing evidence suggest functional roles of subepithelial mesenchymal niche cells in maintaining intestinal stem cells and in modulating the pathogenesis of various intestinal diseases in mammals. A recent...

    Authors: Guoli Zhu and Rongwen Xi
    Citation: Cell Regeneration 2021 10:24
    Content type: Research Highlight Published on:

  24. Ischemic heart disease is one of the main causes of morbidity and mortality in the world. In adult mammalian hearts, most cardiomyocytes are terminally differentiated and have extremely limited capacity of pro...

    Authors: Zhaohui Ouyang and Ke Wei
    Citation: Cell Regeneration 2021 10:14
    Content type: Review Published on:

  25. On January 28 in Nature online, Zheng et al. (Nature, 2021 (Online ahead of print)) reported that they developed an ingenious method of interspecies PSC co-culture system in vitro which unfolded interspecific ...

    Authors: Yiren Qin and Duancheng Wen
    Citation: Cell Regeneration 2021 10:18
    Content type: Research Highlight Published on:

  26. Expression of Mc4r in peripheral organs indicates it has broader roles in organ homeostasis and regeneration. However, the expression and function of Mc4r in the mouse limb and digit has not been fully investi...

    Authors: Hanqian Xu, Hailin Zhang, Yanqing Fang, Huiran Yang, Ying Chen, Chao Zhang and Gufa Lin
    Citation: Cell Regeneration 2021 10:19
    Content type: Research article Published on:

  28. Organoids are three-dimensional self-organizing structures formed by adult tissue stem cells or pluripotent stem cells. They recapitulate cell-cell, cell-niche interactions in tissue development, homeostasis, ...

    Authors: Tiantian Lu, Yiyuan Cao, Peng Zhao, Shengxi Shen and Ying Xi
    Citation: Cell Regeneration 2021 10:21
    Content type: Review Published on:

  29. Heart regeneration is a fascinating and complex biological process. Decades of intensive studies have revealed a sophisticated molecular network regulating cardiac regeneration in the zebrafish and neonatal mo...

    Authors: Lixia Zheng, Jianyong Du, Zihao Wang, Qinchao Zhou, Xiaojun Zhu and Jing-Wei Xiong
    Citation: Cell Regeneration 2021 10:13
    Content type: Review Published on:

  32. The pluripotent stem cells in planarians, a model for tissue and cellular regeneration, remain further identification. We recently developed a method to enrich piwi-1+ cells in Schmidtea mediterranea, by staining...

    Authors: Kaimeng Niu, Hao Xu, Yuanyi Zhou Xiong, Yun Zhao, Chong Gao, Chris W. Seidel, Xue Pan, Yuqing Ying and Kai Lei
    Citation: Cell Regeneration 2021 10:15
    Content type: Research article Published on:

  33. The Wnt/β-catenin signaling pathway appears to be particularly important for bone homeostasis, whereas nuclear accumulation of β-catenin requires the activation of Rac1, a member of the Rho small GTPase family...

    Authors: Wei Shi, Chengyun Xu, Ying Gong, Jirong Wang, Qianlei Ren, Ziyi Yan, Liu Mei, Chao Tang, Xing Ji, Xinhua Hu, Meiyu Qv, Musaddique Hussain, Ling-Hui Zeng and Ximei Wu
    Citation: Cell Regeneration 2021 10:8
    Content type: Research article Published on:

  34. Epigenetic modifications, namely non-coding RNAs, DNA methylation, and histone modifications such as methylation, phosphorylation, acetylation, ubiquitylation, and sumoylation play a significant role in brain ...

    Authors: Jiaqi Sun, Junzheng Yang, Xiaoli Miao, Horace H. Loh, Duanqing Pei and Hui Zheng
    Citation: Cell Regeneration 2021 10:7
    Content type: Review Published on:

  36. As a result of evolution, the ability to repair wounds allows organisms to combat environment insults. Although the general process of wound healing at the tissue level has been described for decades, the deta...

    Authors: Yicong Ma, Jing Xie, Chandra Sugiarto Wijaya and Suhong Xu
    Citation: Cell Regeneration 2021 10:5
    Content type: Review Published on:

  40. The HOX genes are master regulators of embryogenesis that are also involved in hematopoiesis. HOXA9 belongs to a cluster of HOX genes that play extensively studied roles in hematopoiesis and leukemogenesis.

    Authors: Jiahui Zeng, Danying Yi, Wencui Sun, Yuanlin Liu, Jing Chang, Lijiao Zhu, Yonggang Zhang, Xu Pan, Yong Dong, Ya Zhou, Mowen Lai, Guohui Bian, Qiongxiu Zhou, Jiaxin Liu, Bo Chen and Feng Ma
    Citation: Cell Regeneration 2021 10:9
    Content type: Research article Published on:

  42. The rapidly self-renewing epithelium in the mammalian intestine is maintained by multipotent intestinal stem cells (ISCs) located at the bottom of the intestinal crypt that are interspersed with Paneth cells i...

    Authors: Guoli Zhu, Jiulong Hu and Rongwen Xi
    Citation: Cell Regeneration 2021 10:1
    Content type: Review Published on:

  43. Some lower vertebrates such as zebrafish and axolotl have incredible cardiac regenerative potential while mammals have very limited ones. Comparative studies among species have revealed that cardiomyocyte poly...

    Authors: Jing-Wei Xiong
    Citation: Cell Regeneration 2020 9:23
    Content type: Opinion Published on:

  44. Systemic sclerosis is a rare chronic autoimmune disease with extensive microvascular injury, damage of endothelial cells, activation of immune responses, and progression of tissue fibrosis in the skin and vari...

    Authors: Mina Abedi, Sepideh Alavi-Moghadam, Moloud Payab, Parisa Goodarzi, Fereshteh Mohamadi-jahani, Forough Azam Sayahpour, Bagher Larijani and Babak Arjmand
    Citation: Cell Regeneration 2020 9:20
    Content type: Review Published on:

  45. Protein quality control (PQC) systems play essential roles in the recognition, refolding and clearance of aberrant proteins, thus ensuring cellular protein homeostasis, or proteostasis. Especially, continued p...

    Authors: Pengze Yan, Jie Ren, Weiqi Zhang, Jing Qu and Guang-Hui Liu
    Citation: Cell Regeneration 2020 9:22
    Content type: Review Published on:

  46. Three-dimensional cultured organoids have become a powerful in vitro research tool that preserves genetic, phenotypic and behavioral trait of in vivo organs, which can be established from both pluripotent stem ce...

    Authors: Yaqi Li, Peiyuan Tang, Sanjun Cai, Junjie Peng and Guoqiang Hua
    Citation: Cell Regeneration 2020 9:21
    Content type: Review Published on:

  48. Adipose-derived stem cells (ASCs) are considered ideal candidates for both research and cellular therapy due to ease of access, large yield, feasibility, and efficacy in preclinical and clinical studies. Unlik...

    Authors: Nourhan Abu-Shahba, Marwa Mahmoud, Mazen Abdel-Rasheed, Yasmine Darwish, Ahmad AbdelKhaliq, Eman Mohammed, Mahmoud ElHefnawi and Osama Azmy
    Citation: Cell Regeneration 2020 9:18
    Content type: Research article Published on:

  49. Retinoic acid (RA) and 2-phospho-L-ascorbic acid trisodium salt (AscPNa) promote the reprogramming of mouse embryonic fibroblasts to induced pluripotent stem cells. In the current studies, the lower abilities ...

    Authors: Mengdan Zhang, Qian Li, Tingting Yang, Fei Meng, Xiaowei Lai, Lining Liang, Changpeng Li, Hao Sun, Jiaqi Sun and Hui Zheng
    Citation: Cell Regeneration 2020 9:17
    Content type: Report Published on:
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  • ISSN: 2045-9769 (electronic)

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  • Journal Metrics
    2.7 - Cite Score 2021
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